valerie Bertinelli has brain cancer connected to brain cancer but has been a vocal advocate for cancer awareness, partly due to her ex-husband Eddie Van Halen’s battle with cancer. Best known for her roles in One Day at a Time and Hot in Cleveland, Bertinelli is also an Emmy-winning television host. Her memoir, Enough Already, reflects her resilience in facing grief, health challenges, and personal growth, inspiring many with her transparency and advocacy efforts